I am right handed. I can't imagine doing most things with my left arm, which is why I consider myself fortunate that my right arm wasn't amputated after an accident I had when I was 11 years old. Since then, tact in my right arm isn't so good, but I can move it and do everything normally. Still, that is one huge scar and it's probably for life. There are more details to it, but they're gritty and probably not suitable for the site.
I have tried to write with my left hand, but it's so difficult. It's scribbles at best. Still, my left arm is the more flexible one.